Publications by authors named "E Ebbini"
Image-Guided Measurement of Radiation Force Induced by Focused Ultrasound Beams.
IEEE Trans Ultrason Ferroelectr Freq Control
February 2023
Article Synopsis
- The radiation force balance (RFB) method is effective for measuring the acoustic power of ultrasonic transducers but relies on precise alignment between the ultrasound beam and a reflecting cone, particularly critical for focused therapeutic applications.
- The introduction of dual-mode ultrasound arrays (DMUAs) allows for image-guided measurements that enhance alignment and can track cone displacement, thus improving power measurement accuracy.
- Experimental findings show that even slight misalignments can significantly contribute to measurement errors, and real-time tracking of displacement offers a more sensitive and reliable approach for assessing acoustic radiation force, potentially improving dosimetry in focused ultrasound therapies.
Introduction: Peripheral arterial disease (PAD) is an atherosclerotic disease leading to stenosis and/or occlusion of the arterial circulation of the lower extremities. The currently available revascularisation methods have an acceptable initial success rate, but the long-term patency is limited, while surgical revascularisation is associated with a relatively high perioperative risk. This urges the need for development of less invasive and more effective treatment modalities.
View Article and Find Full Text PDFSpatio-Spectral Ultrasound Characterization of Reflection and Transmission Through Bone With Temperature Dependence.
IEEE Trans Ultrason Ferroelectr Freq Control
May 2022
Article Synopsis
- Transcranial focused ultrasound (tFUS) shows potential for treating neurological disorders, with advances in neuromodulation and ablative applications, including epilepsy.
- Modern technologies, like advanced transducers, enhance the effectiveness of tFUS by maximizing the use of the temporal window in the skull, improving safety and targeting within the brain.
- Research demonstrated that various factors, such as temperature and frequency, significantly impact the reflection and transmission of ultrasound through human skull samples, indicating a complex relationship that must be considered for treatment efficacy.
Purpose: High-intensity focused ultrasound (HIFU) is a potential noninvasive thermal ablation method for the treatment of peripheral artery disease. Dual-mode ultrasound arrays (DMUA) offer the possibility of simultaneous imaging and treatment. In this study, safety and feasibility of femoral artery robot-assisted HIFU/DMUA therapy was assessed.
View Article and Find Full Text PDFArticle Synopsis
- Carotid bodies are chemoreceptors that help regulate breathing by monitoring blood oxygen, carbon dioxide, and pH levels, and their increased activity is linked to high blood pressure.
- Researchers used a dual-mode ultrasound array system to safely ablate the carotid bodies in spontaneously hypertensive rats, utilizing advanced imaging techniques for precise targeting and monitoring of the treatment.
- The study found that targeting the carotid bodies with focused ultrasound could potentially lower blood pressure, indicating the need for further research in larger animal models and clinical trials in humans.