[Vascular mechanisms in Meniere's disease].

Meniere's disease (MD) is chronic multifactorial medical condition caused by endolymphatic hydrops, which etiology is unclear. This review highlights possible vascular mechanisms of MD. Impairment of vascular regulation, further ischemic damage of labyrinth and venous drainage pathology could lead to endolymphatic hydrops.

[Improvement of laboratory diagnostics of cholera due to genetically altered (hybrid) variants of cholera Vibrio biovar El Tor].

Aim: Improvement of laboratory diagnostics of cholera taking into the account appearance of hybrid variants of cholera vibrio El Tor biovar in the 1990s.

Materials And Methods: Phenotypic and molecular-genetic properties of typical toxigenic (151 strains) and hybrid (102 strains) variants of El Tor biovar cholera vibrios, isolated in the Caucuses in 1970-1990 and 1993-1998, respectively, were studied. Toxigenicity gene DNA fragments, inherent to El Tor biovars or classic, were detected by using a reagent kit "Genes of Vibrio cholerae variant ctxB-rstR-rstC, REF" developed by us.

[Analysis of sequences of ITS1 internal transcribed spacer and 5.8S ribosome gene of Malus species].

The nucleotide sequence of the ITS1-5.8S ribosomal DNA spacer fragment was determined for 41 samples of the Malus species. The total length of compared sequences ranged from 389 to 392 bp.

[Clinical peculiarities of diagnostics of sensorineural loss of hearing and deafness in children].

The clinical features of various subjective and objective methods for the study of the hearing function were evaluated based on the results of examination of 46 children presenting with sensorineural hearing loss and deafness. The factors that influence the effectiveness and quality of diagnostics of sensorineural loss of hearing in the children were elucidated.

[The hearing function in the patients presenting with the intralabyrinthine distribution of giant cholesteatoma].

The objective of the present study was to evaluate the state of the hearing function in the patients presenting with the intralabyrinthine distribution of giant cholesteatoma before and after the surgical treatment based on the results of examination by the subjective and objective methods. The possibility of preservation of the hearing function after the surgical intervention has been demonstrated.