The impact of hypoalbuminemia on the long-term prognosis of patients with acute heart failure: The modifying role of carbohydrate antigen 125.

Aims: Hypoalbuminemia is frequently found in patients with heart failure (HF), associated with higher morbimortality in acute HF (AHF). Moreover, Carbohydrate Antigen 125 (CA125) is elevated in most of the AHF patients. In this cohort of patients admitted for AHF, our objective was to evaluate the association between hypoalbuminemia and long-term outcomes, including mortality and HF readmissions, stratified by CA125 concentration.

Detectable use of ENSO information on crop production in Southern Africa.

People have known that El Niño events are associated with low rainfall in Southern Africa for a century, and seasonal rainfall forecasts are now available in agricultural advisories for farmers. While there is abundant theory as to how farmers might (or should) use seasonal rainfall information on their farms, little is known about whether this information has been widely used or has had widespread benefit. In this study, we use subnational data on cropping area and yield to see if we can detect any macro-level patterns in agricultural choices or outcomes that are related to knowledge of the El Niño Southern Oscillation or seasonal forecast information in Southern Africa.

Retinal Microperimetry as a Novel Tool for Early Detection of Subclinical Cognitive Dysfunction and Brain Damage in Type 1 Diabetes: A Pilot Study.

Context: Retinal microperimetry (MPR) is a non-invasive method that measures retinal light sensitivity (RS) and gaze fixation stability (GFS). MPR has been described as a marker of cognitive impairment in people with Type 2 diabetes, but it has never been assessed in people with Type 1 diabetes (T1D). Our group described subclinical cognitive alterations, structural brain differences, and increased levels of light chain neurofilament (NfL) in people with T1D and impaired awareness of hypoglycaemia.