[A rare case of large-cell gastric lymphoma in a patient with chronic lympholeucosis].

Chronic lympholeucosis (CLL) is a B-cell lymphoproliferative disease, the morphological substrate of which is a clone of lymphocytes similar in size and morphology to normal mature lymphocyte and similar in immunophenotype to B lymphocytes at late stages of differentiation. The occurrence of large-cell lymphoma against the background of B-CLL is called Richter syndrome. A new tumor may occur in lymph nodes, the spleen, the liver, and the gastrointestinal tract (GIT).

[Neocytapheresis in donors].

Various techniques and blood separators were employed to obtain therapeutic doses of immature erythrocytes (neocytes) from blood of 18 donors. Regimens of neocyte apheresis, preparative efficiency of blood separators, morphofunctional and biophysical characteristics of neocytes obtained were compared. Neocyte apheresis shows promise for hematological patients dependent on red cells transfusion.

[Comprehensive diagnosis of cancer of the ovaries].

Combined examination of 96 patients with different gynecological diseases included methods of ultrasound tomography, scintigraphy of the small pelvis with 99mTc-pyrophosphate, immunoscintigraphy and radioimmunoassay for determination of the blood level of CA 125. New diagnostic methods for ovarian cancer using 131I labeled monoclonal antibodies and an algorithm for data processing were developed. Of 96 patients 39 had ovarian cancer, 6 patients--uterine tumors, and 51 patients (controls) with nontumorous and benign lesions of the ovaries and uterus.