Publications by authors named "E E Ligeon"
In this study the morphologic and functional changes were compared after irradiation (single dose, 15 Gy) of rat submandibular salivary glands. Before and 1-10 days after local irradiation of the gland region, samples of submandibular saliva were collected after stimulation by pilocarpine. At the same time-points and also 3 h postirradiation submandibular glands were carefully extirpated and prepared for histocytologic examination (LM, TEM).
View Article and Find Full Text PDFThe effect of a single local dose of 15 Gy on salivary gland function in male Albino Wistar rats was compared with the effect of two doses of 7.5 Gy. The intervals chosen were 0-24 h and 1 week.
View Article and Find Full Text PDFThe aim of this study was to monitor composition and rate of secretion of rat parotid and submandibular/sublingual saliva following local single doses of X-rays ranging from 5 to 20 Gy. Pilocarpine-stimulated samples of parotid and submandibular/sublingual saliva were simultaneously collected with miniaturized Lashley cups before and 1-30 days after irradiation. The lag phase (period between injection of pilocarpine and start of the secretion) and flow rate were recorded and the concentrations of sodium, potassium, calcium, phosphate, and amylase were measured.
View Article and Find Full Text PDFThe aim of this study was to monitor changes in the composition and the rate of secretion of rat whole, parotid and submandibular/sublingual saliva after local irradiation of the salivary gland region with a single dose of 10 Gy. Before and 1-30 days after irradiation, saliva samples were collected after stimulation with pilocarpine. Maximum changes in the latent period, the flow rate and the composition of parotid and submandibular/sublingual saliva were observed three days after a radiation dose of 10 Gy.
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