Consumption of calcium carbide-ripened banana by pregnant rats may programme for infertility in female offspring.

One of the substances used in force ripening fruits is commercial grade calcium carbide (CaC2) which contains impurities such as arsine and this has been associated with low birth weight and fetal loss. There is thus a need to further investigate additional risks on offspring. This study was thus designed to evaluate the possible effects of maternal consumption of banana pulp force ripened with CaC2 on the offspring.

Prenatal and early postnatal food restrictions cause changes in brain oxidative status and orexigenic/anorexigenic hormones in the offspring of rats: prevention by quercetin and kaempferol.

Brain oxidative signaling pathways have been identified as important targets for alleviating food deprivation-induced changes in metabolic gate-ways. Previous studies have shown that prenatal and early postnatal malnutrition alters leptin and ghrelin signaling via oxidative pathways. Thus, it has been hypothesized that agents with antioxidant properties might be beneficial for the mitigation of prenatal and early postnatal food scarcity-induced oxidative damage.

Consumption of Aqueous Leaf Extract During Lactation May Improve Metabolic Homeostasis in Young Adult Offspring.

Background And Objective: Medicinal plants constitute a fundamental component of the traditional healthcare system in rural communities throughout Africa and Gongronema latifolium (GL), is widely trusted in Nigeria to have strong nutritional and medicinal values. This study was done to determine the effect of maternal consumption of GL during lactation in young adult offspring.

Materials And Methods: Twenty four female albino Wistar rats were used for this study and were randomly assigned to four (4) groups.

Altered gestational outcomes and delayed pubertal onset in prenatally and early postnatally food restricted male and female rats: mitigation by quercetin and kaempferol.

Nutrigenomic malnutrition during pregnancy and early postnatal life has serious consequences on original organ-programing, growth pattern, puberty and quality of life. The aim of this was to investigate the effect of two notable flavonoids, quercetin and kaempferol, with nutrigenomic potentials on prenatal and early postnatal food restrictions or both on gestational outcomes and the onset of puberty in male and females Wister rats. In three sets of experiments consisting of prenatal, postnatal food deprivations or both, rats were distributed into various treatment groups (n = 6).

The Role of Fine Needle Aspiration Cytology in Triple Assessment of Patients with Malignant Breast Lumps.

Background: Breast cancer is the leading female malignancy in the world and now the most common cancer in Nigeria. The evaluation of patients with breast cancer requires stepwise diagnostic approach to achieve a combined diagnostic information required to make an enhanced decision on how best to approach management. The aim of this study is to evaluate the role of fine needle aspiration cytology (FNAC) in the triple assessment of patients with malignant breast lumps in our center.