Publications by authors named "E E H van Wegen"
Background: Individuals with advanced multiple sclerosis (MS) have complex care requirements and are more likely to use long-term facilities. This study determined the associations between mood and social care-related quality of life (SCRQOL), and health-related quality of life (HRQOL) and examined the association between HRQOL and SCRQOL.
Methods: Baseline data from a cohort study were used.
Article Synopsis
- The study aimed to evaluate the effectiveness of caregiver-mediated exercises combined with telerehabilitation compared to usual care in improving self-reported mobility after a subacute stroke.
- A total of 41 patient-caregiver pairs participated in an 8-week program involving mobility exercises, with results showing no significant difference in mobility outcomes between the intervention and control groups.
- However, secondary outcomes indicated benefits for caregivers, including improvements in their quality of life and reduced depression, suggesting that while mobility did not improve, caregiver support may enhance their well-being.
Non-pharmacological interventions, including cognitive-behavioral therapy (CBT), non-invasive brain stimulation (NIBS), electroconvulsive therapy (ECT), light therapy (LT), and physical rehabilitation/exercise, have shown promise as effective approaches to treat symptoms of depression and anxiety in individuals with Parkinson's disease (PD). In this narrative literature overview, we discuss the state-of-the-art regarding these treatment options and address future perspectives for clinical practice and research. Non-pharmacological interventions hold promise to treat depression and anxiety in PD.
View Article and Find Full Text PDFIntroduction: Exercise therapy may increase brain-derived neurotrophic factor (BDNF) levels and improve clinical outcomes in people living with Parkinson's disease (PD). This systematic review was performed to investigate the effect of exercise therapy on BDNF levels and clinical outcomes in human PD and to discuss mechanisms proposed by authors.
Method: A search on the literature was performed on PubMed up to December 2023 using the following key words: Parkinson's disease AND exercise, exercise therapy, neurological rehabilitation AND brain-derived neurotrophic factor, brain-derived neurotrophic factor/blood, brain-derived neurotrophic factor/cerebrospinal fluid AND randomized clinical trial, intervention study.