[Dependence of the cytogenetic adaptive response in the rat bone marrow cells on the dose of chronic gamma irradiation in vivo].

The induction of chromosome aberrations in bone marrow cells of rats exposed to chronic gamma-irradiation and subsequently to acute gamma-irradiation was studied. Adult male rats were exposed ot 3-40 cGy (2.9 cGy/day) of chronic gamma-irradiation (adaptive dose) and subsequently to 4 or 6 Gy of gamma-rays (47 cGy/min, challenge dose).

Action of chronic irradiation on the cytogenetic damage of human lymphocyte culture.

The action of chronic irradiation (dose rate 2.9 Gy/day) on human lymphocyte culture was investigated. Whole blood was irradiated at 37 degrees C.

[Induction of cytogenetic damage to rat bone marrow cells by combined exposure to chronic and acute gamma radiation].

The combined influence of various doses of chronic irradiation (0.029 Gy/day) followed by acute irradiation at doses of 4 and 6 Gy (0.47 Gy/min) on the frequency of chromosomal aberrations in rat bone-marrow cells was studied.

[Induction of cytogenetic damage in Chinese hamster cells after combined exposure to low doses of gamma-radiation and various chemical and physical agents].

Supersensitivity of Chinese hamster cells to low doses of gamma-radiation (dose range 5 to 50 cGy) was revealed by means of the cytokinesis-block micronucleus test. Treating these cells with caffeine (repair inhibitor) and mercaptoethylamine (radioprotector) and exposing them to secondary radiation emitted by protons with an energy of 70 GeV showed that this supersensitivity is associated with the absence of cytogenetic repair. When cells at the G2 phase received preliminary doses of 30 and 75 cGy before being irradiated at 150 cGy, the incidence of cytogenetic damage decreased, i.

[Effect of chronic neutron irradiation on fibroblast cell culture in Chinese hamster].

The effect of monoenergy (30 Gev) neutron radiation on Chinese hamster fibroblasts has been studied by micronuclear test. It has been shown that in the range of doses up to 60 cGy RBE is equal to unity.