Publications by authors named "E E Baron"
Purpose: The respiratory rate-oxygenation (ROX) index is used to predict high-flow nasal cannula (HFNC) success in acute respiratory failure, including in Coronavirus disease 2019 (COVID-19) patients. However, no study has described its performance to predict failure of alternating sessions of noninvasive ventilation (NIV) and HFNC in severe COVID-19 patients.
Material And Methods: We conducted a monocentric retrospective cohort study.
Background: Missing data decreasing study power and introducing bias, thereby undermining a registry's ability to draw valid inferences. We evaluated how missing data are reported and addressed in heart transplantation (HT) studies using the United Network for Organ Sharing (UNOS) database.
Methods: We conducted a systematic literature search of Medline from January 1, 2018 through August 22, 2023 and included studies that used the UNOS database to evaluate adult (≥18 years) de novo HT recipients.
Article Synopsis
- Continuous renal replacement therapy (CRRT) is vital for severe acute kidney injury in ICU, but filter clotting complicates treatment, and regional citrate anticoagulation (RCA) is a preferred method due to its lower bleeding risks.
- This study aims to compare two targets for post-filter ionised calcium (iCa) levels during RCA-CRRT—0.25-0.35 mmol/L versus 0.35-0.45 mmol/L—to see if a higher target can prevent clotting without increasing adverse effects.
- The trial is ethically approved, includes informed consent from patients, and results will be shared in academic venues, ensuring data protection and confidentiality.
Article Synopsis
- The study investigates the demographic history of France using genotype datasets from individuals in Northern France, revealing significant population structure and differentiation in regions like Brittany and the Loire basin.
- The research highlights a connection between the ancestry of local populations and genetic variations, particularly indicating a distinction in shared ancestry related to Neolithic and steppe populations.
- Findings suggest the necessity of studying local demographics to better comprehend the distribution of genetic variants and their role in the prevalence of diseases among populations in Brittany and neighboring areas.