Optoelectronic Readout of Single Er Adatom's Electronic States Adsorbed on the Si(100) Surface at Low Temperature (9 K).

Integrating nanoscale optoelectronic functions is vital for applications such as optical emitters, detectors, and quantum information. Lanthanide atoms show great potential in this endeavor due to their intrinsic transitions. Here, we investigate Er adatoms on Si(100)-2×1 at 9 K using a scanning tunneling microscope (STM) coupled to a tunable laser.

Nanovectorization of Ivermectin to avoid overdose of drugs.

Ivermectin is an antiparasitic drug that results in the death of the targeted parasites using several mechanical actions. While very well supported, it can induce in rare cases, adverse effects including coma and respiratory failure in case of overdose. This problem should be solved especially in an emergency situation.

A potential solution to avoid overdose of mixed drugs in the event of Covid-19: Nanomedicine at the heart of the Covid-19 pandemic.

Since 2020, the world is facing the first global pandemic of 21st century. Among all the solutions proposed to treat this new strain of coronavirus, named SARS-CoV-2, the vaccine seems a promising way but the delays are too long to be implemented quickly. In the emergency, a dual therapy has shown its effectiveness but has also provoked a set of debates around the dangerousness of a particular molecule, hydroxychloroquine.

Two-Dimensional Functionalized Ultrathin Semi-Insulating CaF Layer on the Si(100) Surface at a Low Temperature for Molecular Electronic Decoupling.

The ability to precisely control the electronic coupling/decoupling of adsorbates from surfaces is an essential goal. It is important for fundamental studies not only in surface science but also in several applied domains including, for example, miniaturized molecular electronic or for the development of various devices such as nanoscale biosensors or photovoltaic cells. Here, we provide atomic-scale experimental and theoretical investigations of a semi-insulating layer grown on a silicon surface via its epitaxy with CaF.

Theoretical study of ciprofloxacin antibiotic trapping on graphene or boron nitride oxide nanoflakes.

Reactions between the antibacterial fluoroquinolone agent ciprofloxacin (CIP) and organic hydrophilic nanoflakes (graphene oxide and boron nitride oxide) have been studied in aqueous medium using density functional theory (DFT), time-dependent density functional theory (TD-DFT), and molecular dynamics (MD) simulations. We found that CIP molecules in π-π electron donor-acceptor (EDA) reaction preserve their optical properties in water when adsorbed on hydrophilic nanoflakes. Moreover, MD calculations aimed at studying the diffusive translocation of CIP to lipid membrane showed that the choice of the hydrophilic nanovectors is primordial to stabilize the molecule on the cellular membrane and improve cytotoxic effects.