Influence of boundary conditions on the behavior of laminated glass curved beam with delamination effect: An experimental and numerical investigation.

The delamination phenomena of laminated glass structures are issues that are not perfectly understood and remain problematic to predict due to the nonlinearity of the geometric response. A research study is undertaken to investigate the behavior of laminated glass curved beams with initial delamination exposed to different boundary conditions. A mathematical model which contains nonlinear field equations and boundary conditions is developed.

The relationship between lymphocyte DNA damage, coronary artery disease, and blood trace elements.

Somatic DNA damage and causative factors (occupational exposures, foods, habits, etc.) are thought to contribute to the pathogenesis of atherosclerosis, although knowledge about their role in coronary artery disease (CAD) is still insufficient. This study aimed to determine the effects of lymphocyte-DNA damage and blood trace element concentrations on CAD.

The Potential Role of and Genetic Variations and Lifestyle Factors on Clozapine and N-DesmethylClozapine Plasma Levels in Schizophrenia Patients.

Background: Despite its advantages over other antipsychotics, for treatment-resistant schizophrenia, clinical use of Clozapine (CLZ) is challenging by its narrow therapeutic index and potentially life-threatening dose-related adverse effects.

Research Design And Methods: As the potential role in CLZ metabolism is assigned to CYP1A2 enzyme and consequently Cytochrome P450 oxidoreductase (POR) their genetic variations might help to determine CLZ levels in schizophrenia patients. For this purpose, 112 schizophrenia patients receiving CLZ were included in the current study.