Publications by authors named "E Dugast"
An important body of literature suggests that exerting intense cognitive effort causes mental fatigue and can lead to unhealthy behaviors such as indulging in high-calorie food and taking drugs. Whereas this effect has been mostly explained in terms of weakening cognitive control, cognitive effort may also bias behavioral choices by amplifying the hedonic and emotional impact of rewards. We report parallel findings with animals and humans supporting this hypothesis.
View Article and Find Full Text PDFImpulsivity dimensions have been shown to be associated with smoking status and tobacco use disorder severity. However, it is important to determine the specific impulsivity traits associated with smoking relapse. This study aimed at investigating the associations between impulsivity traits and smoking cessation success among adult smokers at 12 months after a quit attempt.
View Article and Find Full Text PDFExposure to highly palatable food is believed to induce behavioral and neurobiological changes that may produce addiction-like behavior and increase the risks of obesity and overweight. Studies in rodents have led to conflicting results suggesting that several factors such as sex and age of exposure contribute to the development of maladaptive behaviors towards food. In addition, it is not clear whether effects of exposure to highly palatable diets (HPD) persist after their discontinuation, which would indicate long-term risks to develop addiction-like behavior.
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- A pilot study investigated the gut and oral microbiota in multiple sclerosis (MS) patients and found significant bacterial alterations compared to healthy volunteers (HV).
- The analysis revealed decreased diversity and specific bacteria depletion in MS patients, along with enrichment of inflammation-associated bacteria and altered microbial pathways.
- A distinctive oral metabolite signature was identified in MS patients, which has high specificity for discriminating them from HV and patients with rheumatoid arthritis, suggesting the potential for future research on oral microbiota in autoimmune diseases.
Multiple sclerosis is an autoimmune disease of the central nervous system. Yet, the autoimmune targets are still undefined. The extracellular e1 sequence of KCNJ10, the inwardly rectifying potassium channel 4.
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