Publications by authors named "E Do Linh San"

There is an unmet clinical need for pharmacologic treatment for metabolic dysfunction-associated steatotic liver disease (MASLD). Hepatocyte cell death is a hallmark of this highly prevalent chronic liver disease, but the dominant type of cell death remains uncertain. Here we report that ferroptosis, an iron-catalyzed mode of regulated cell death, contributes to MASLD.

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With the advancement of modern medicine and the prolonged survival of critically ill patients, unusual organisms are increasingly emerging. Initially found in the environment, these rare organisms started presenting as human pathogens, causing significant morbidity and mortality. Here, we present a rare case of disseminated fungemia and  bacteremia in a patient with parapneumonic effusion and ruptured liver abscess.

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Article Synopsis
  • Adalimumab has become a more affordable option for treating inflammatory bowel disease (IBD) since its patent expiration, but adhering to the medication is crucial for its effectiveness.
  • This study analyzed the relationship between high refill-adherence (defined as medication possession ratio of 80% or more) and disease activity in IBD patients using a retrospective approach.
  • Results showed that patients with high adherence had significantly lower rates of active disease, emphasizing the importance of sticking to adalimumab therapy for better health outcomes and potentially reducing the need for costlier alternatives.*
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Unprotected iron can rust due to oxygen exposure. Similarly, in our body, oxidative stress can kill cells in an iron-dependent manner, which can give rise to devastating diseases. This type of cell death is referred to as ferroptosis.

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The purpose of this descriptive study was to explore the understanding of occupational justice and occupational therapy's role among staff members working within organizations serving persons experiencing homelessness. A survey was developed to determine if staff ( = 43) understood what occupational therapists can do to help persons experiencing homelessness. Responses were split almost equally between agree/strongly agree and disagree/strongly disagree.

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