[Lymphocyte populations and subpopulations in peripheral blood of pregnant women with pre-eclampsia].

Aim: To investigate the changes of lymphocyte populations and subpopulations in peripheral blood of pregnant women suffering preeclampsia.

Material And Methods: By means of flowcytometry the following lymphocyte populations and subpopulations were determined in peripheral blood of 37 pregnant women, of whom 12 had preeclampsia and 25 had normal pregnancy pespectively: Total lymphocyte count CD19+ (B-lymphocytes), CD2+ (Total T-lymphocytes), CD3+ (Immunocompetent T-lymphocytes) CD3+CD4+ (T-helpers), CD3+CD8+ (Suppressor-cytoxic T-lymphocytes), CD4+/CD8+ ratio, Lymphocyte subpopulations with predominant killer activity: CD8-CD56+, CD8+CD56+ and activated immunocompetent T-lymphocytes (CD3+HLADR+).

Results: In patients with preeclampsia a T-helper increase and relative T-suppressor cytotoxic decrease was found.