Characterization of the potential allergenicity of enzymatically hydrolyzed casein in Balb/c mouse model.

Bovine casein is a major allergen present in cow milk to induce anaphylaxis. In this study, the potential allergenicity of enzymatically hydrolyzed casein (HC) was evaluated based on in vitro and in vivo. The results showed that Alcalase and Protamex treatment (AT, PT) reduced the potential allergenicity of CN, with the greatest reductions of 68.

Bovine parainfluenza virus type 3 infections induce ER stress-mediated autophagy to facilitate virus replication.

Bovine Parainfluenza Virus Type 3 (BPIV3) serves as a crucial pathogen in cattle, adept at triggering severe respiratory symptoms. This investigation explores the intricate interplay of endoplasmic reticulum stress (ER stress), unfolded protein response (UPR), and autophagy upon BPIV3 infection. In this study, we initially confirm a substantial increase in glucose regulatory protein 78 (GRP78) expression, accompanied by noticeable morphological changes and significant expansion of the ER lumen observed through transmission electron microscopy upon BPIV3 infection.

Hot Deformation Behavior and Mechanisms of SiC Particle Reinforced Al-Zn-Mg-Cu Alloy Matrix Composites.

A systematic and comprehensive analysis of the hot deformation and mechanisms of SiC particle-reinforced aluminum matrix composites is significant for optimizing the processing of the composites and obtaining the desired components. Based on this, related research on 11 vol% SiCp particle-reinforced 7050Al matrix composites was carried out. Hot compression experiments were carried out on the Gleeble-3500 thermal simulator to study the hot deformation behavior of composites at the temperature of 370-520 °C and strain rate of 0.

Comparative metabolomic analysis and antigenicity comparison of cow milk and enzymatically treated cow milk.

Background: Amino acids (AAs) are important protein building blocks that play a critical role in the function of the immune system. However, comprehensive comparative metabolomics and antigenicity analyses of cow milk (CM) and enzymatically treated CM are relatively scarce. This study analyzed the AAs in the CM and Flavourzyme-treated milk groups (FT), and their antigenicity was also explored.