Publications by authors named "E Derrick"

Natural killer (NK) cells play a vital role in innate immunity and show great promise in cancer immunotherapy. Traditional sources of NK cells, such as the peripheral blood, are limited by availability and donor variability. In addition, in vitro expansion can lead to functional exhaustion and gene editing challenges.

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A spatial-genomic analysis reveals that bird species living closer to humans have higher diversity of the pathogen Campylobacter and its antimicrobial resistance genes. This suggests that urbanization could promote pathogen transmission among wild animals and, potentially, humans.

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Article Synopsis
  • CAR T cell therapy has been effective for treating blood cancers but struggles with solid tumors due to challenging tumor microenvironments.
  • Research indicates that CAR T cells with a 'stem-like' phenotype and greater mitochondrial mass have better treatment outcomes.
  • The study highlights that overexpressing the transcription factor FOXO1 in CAR T cells can enhance their fitness and effectiveness against solid tumors by promoting a more beneficial metabolic state.
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Objective: Essential vocal tremor (EVT) manifests as nearly rhythmic modulations of fundamental frequency (f) and intensity and causes a shaky voice. Although research on behavioral therapy for EVT is limited, previous studies have shown that a breathy voice reduces the perception of simulated EVT and might be an effective compensatory strategy. The current study aimed to measure the acoustical and perceptual effects of a breathy voice strategy in speakers with EVT.

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