Publications by authors named "E Denny"

Article Synopsis
  • Endometriosis affects 1 in 10 women, often leading to surgery for persistent pain, but symptoms frequently recur post-operation, creating uncertainty about the most effective hormonal treatments.
  • A study was conducted across 34 UK hospitals to compare the effectiveness of long-acting progestogen therapy with the combined oral contraceptive pill in preventing pain recurrence and improving quality of life after surgery.
  • Results showed both treatment options reduced pain compared to pre-surgery levels, but no significant difference in effectiveness was found between the two, although fewer follow-up procedures were needed for those on long-acting progestogen.
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Introduction: Tumor necrosis factor (TNF-α) is known to be associated with chronic inflammation, and its expression has been shown to increase in advanced cancers. Chronic inflammation is a characteristic feature of oral submucous fibrosis (OSMF), which is a potentially malignant disorder (PMD). Squamous cell carcinoma (SCC) is associated with considerable mortality and morbidity and an early detection or monitoring would greatly help in achieving an effective cure.

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The Wood-Ljungdahl pathway (WLP) is a key metabolic component of acetogenic bacteria where it acts as an electron sink. In Archaea, despite traditionally being linked to methanogenesis, the pathway has been found in several Thermoproteota and Asgardarchaeota lineages. In Bathyarchaeia and Lokiarchaeia, its presence has been linked to a homoacetogenic metabolism.

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