Publications by authors named "E Delfini"
Purpose: To describe the unexpected one-year course of a probable Tobacco Alcohol Optic Neuropathy (TAON) and the unprecedented Laser Speckle Flowgraphy (LSFG) assessment.
Case Report: A 49-year-old Caucasian man with no family history of visual impairment referred because of unilateral and painless visual acuity (VA) decrease in the right eye (RE). Also, color vision and visual evoked potentials were unilaterally altered.
Article Synopsis
- A new case of MFRP-related syndrome was reported in a 33-year-old woman with significant eye conditions, including posterior microphthalmos and retinal degeneration, followed over a 30-month period.
- Comprehensive ophthalmological assessments and genetic testing revealed a homozygous mutation in the MFRP gene, which is linked to the observed symptoms.
- The study also reviewed existing literature and found a diverse range of disease expression among 17 reported cases, highlighting variability in symptoms and progression despite similar genetic mutations.
Background: Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) allows selective replacement of the endothelium. Post-operative haze and particles can affect the interface quality and, ultimately, visual outcome. In this study, we evaluated DSAEK interface with in vivo laser confocal microscopy (LCM) in order to: (i) correlate interface status with best corrected visual acuity, and (ii) with time from surgery; (iii) correlate interface particle number with best corrected visual acuity.
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- New spectral-domain OCT devices show higher retinal thickness values compared to older time-domain OCTs, prompting a study to compare manual measurements between the two technologies.
- Six eyes were analyzed using Stratus and Cirrus OCT devices, measuring retinal thickness at various points and assessing the reproducibility of these measurements using statistical methods like ICC and Bland-Altman plots.
- Results indicated significant differences in retinal thickness values between Stratus and Cirrus measurements, but high reproducibility was found within the manual measurements, suggesting they can be used interchangeably for comparisons.
Article Synopsis
- The study aimed to evaluate the accuracy and consistency of central corneal thickness (CCT) measurements using three different methods: swept-source anterior segment optical coherence tomography (AS-OCT), spectral-domain retinal OCT, and ultrasound pachymetry (USP).
- The analysis involved 50 healthy volunteers and utilized statistical methods to compare CCT measurements and assess repeatability, revealing that AS-OCT provided the most consistent results.
- Although CCT measurements from all three methods showed strong correlations, they were not identical, highlighting AS-OCT’s excellent repeatability in producing pachymetric maps.