Implementing control measures.

Implementation is the means by which a favorable infection control policy leads to a favorable result (low infection rate). Determination of endemic infection rates by traditional surveillance (outcome surveillance) may, in many situations, be a relatively insensitive method for identifying suboptimal implementation practices. Surveillance of the practices themselves (process surveillance) may identify situations likely to lead to unfavorable results and thus provide early feedback to personnel.

A comparison of the onset of action and therapeutic efficacy of amoxapine and amitriptyline.

A total of 61 moderately to severely depressed outpatients were treated for four weeks with either amoxapine (a dibenzoxapine tricyclic) or amitriptyline. This double blind study showed that amoxapine was as effective as amitriptyline and had an earlier onset of action. Maximum doses used were 300 mg of amoxapine and 150 mg of amitriptyline.