LDL cholesterol levels and treatment intensity in secondary prevention of patients with ischemic heart disease in the primary care setting: a real-world data registry study.

Background: Monitoring LDL cholesterol (LDL-C) and prescribing appropriate treatment is crucial for secondary prevention in primary care.

Aim: We studied LDL-C levels and treatments for ischemic heart disease patients according to target recommendations and assessed factors influencing prescribed drug intensity.

Design & Setting: We examined electronic health records of patients with ischemic heart disease from three primary care centers.

Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases.

Background And Objectives: Plasma biomarkers of Alzheimer disease (AD), neuroinflammation, and neurodegeneration are increasingly being used in clinical trials for diagnosis and monitoring of dementia. However, their association with longitudinal structural brain MRI changes, an important outcome measure across neurodegenerative and cerebrovascular diseases, is less known. We investigated how baseline plasma biomarkers reflect MRI markers of progression over time in patients with neurodegenerative and cerebrovascular diseases.

A randomised controlled trial to evaluate the efficacy of a multi-step oral hygiene product intervention to improve oral health in partial denture wearers.

Objectives: This study was designed to evaluate the effectiveness of a multi-step oral hygiene intervention among removal partial denture (RPD) wearers.

Methods: A 12-week, single-blind, randomised, 2-armed, parallel-group, controlled trial was conducted with 49 RPD-wearing participants with mild-moderate gingivitis. The intervention group received stannous fluoride toothpaste, sodium fluoride mouth rinse, and an antibacterial denture cleanser foam.

Diagnosis and Treatment of Gestational Non-Epithelial Ovarian Cancer: A Systematic Review.

Background/aim: Ovarian cancer is categorized into epithelial ovarian cancer and non-epithelial ovarian cancer (NEOC), with NEOC accounting for approximately 10% of cases, predominantly affecting young women and adolescents. The incidence of gestational ovarian cancer is expected to rise in developed nations due to delayed childbearing. NEOC in pregnancy presents various risks, including spontaneous abortion, ventriculomegaly, respiratory distress, and maternal-fetal mortality.

Antimicrobial resistance and epidemiological aspects of Neisseria gonorrhoeae in the province of Lleida, Spain (2017-2024).

Introduction: Neisseria gonorrhoeae (NG) is one of the main causes of sexually transmitted infections and it is reaching high resistance levels worldwide. The aim of this study was to describe the antibiotic resistance, incidence and circulating sequence types of NG in the province of Lleida (Spain).

Methods: A total of 487 NG isolates were included in the study (2017-2024).