Publications by authors named "E De Leeuw"
Background: Culture and its practice is a recognised, but not well understood factor, in Aboriginal health and wellbeing. Our study aimed to explore how health and wellbeing are phenomenologically connected to cultural practices, foods, medicines, languages, and Country, through the platform of 'on-Country' camps facilitated by Aboriginal cultural knowledge holders in NSW, Australia.
Methods: Our study is based on a collaboration between knowledge holders from freshwater and saltwater cultures, and Aboriginal and non-Aboriginal researchers.
This article situates the field of health promotion in its current cutting-edge agendas around health and wellbeing; social and other determinants of health; complexity and its associated sciences; planetary health; and inclusion and diversity. However, it is also proposed that there are emergent dimensions that should be placed more deliberately on the agendas of health promotion research and practice. The piece offers three dimensions for noting health promotion futures: a cognitive, spatial and temporal one.
View Article and Find Full Text PDFBackground: Dysregulated innate immune responses underlie multiple inflammatory diseases, but clinical translation of preclinical innate immunity research in mice is hampered by the difficulty of studying human inflammatory reactions in an context. We therefore sought to establish human inflammatory responses in NSG-QUAD mice that express four human myelopoiesis transgenes to improve engraftment of a human innate immune system.
Methods: We reconstituted NSG-QUAD mice with human hematopoietic stem and progenitor cells (HSPCs), after which we evaluated human myeloid cell development and subsequent human responses to systemic and local lipopolysaccharide (LPS) challenges.