Publications by authors named "E De Graaf-Roelfsema"

Background: Adrenal gland ultrasonographic measurements are useful in clinical evaluation of patients with adrenal dysfunction in several species. In human healthy neonates, the ultrasonographic size of the adrenal glands decreases during the first days of life. Ultrasonography of adrenal glands was demonstrated to be feasible in neonatal foals.

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Article Synopsis
  • Insulin resistance in horses is becoming an important area of study due to its link to various equine health issues, prompting research on treatments like L-carnitine.
  • The study involved six warmblood geldings and aimed to see how L-carnitine affects insulin sensitivity and other metabolic markers over 28 days, using rigorous testing methods.
  • Results showed that while insulin sensitivity didn't improve, L-carnitine significantly increased plasma leptin and acylcarnitine levels, indicating a need for more research on its potential benefits for metabolic disorders in horses.
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Horses are used for a wide variety of purposes from being used for recreational purposes to competing at an international level. With these different uses, horses have to adapt to numerous challenges and changes in their environment, which can be a challenge itself in continuously safeguarding their welfare. The objective of this study was to assess the prevalence of health disorders with clinical examination and identify possible risk factors of health disorders affecting horse welfare in professional husbandry systems in the Netherlands.

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One of the principal components of equine metabolic syndrome (EMS) is hyperinsulinaemia combined with insulin resistance. It has long been known that hyperinsulinaemia occurs after the development of insulin resistance. But it is also known that hyperinsulinaemia itself can induce insulin resistance and obesity and might play a key role in the development of metabolic syndrome.

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