Publications by authors named "E David"

Background: The use of local consolidative therapy (LCT) in patients with oligometastatic non-small cell lung cancer (NSCLC) is rapidly evolving, with a preponderance of data supporting the benefits of such therapeutic approaches incorporating pulmonary resection for appropriately selected candidates. However, practices vary widely institutionally and regionally, and evidence-based guidelines are lacking.

Methods: The Society of Thoracic Surgeons assembled a panel of thoracic surgical oncologists to evaluate and synthesize the available evidence regarding the role of pulmonary resection as LCT.

View Article and Find Full Text PDF

Introduction: Chronic hand eczema (CHE) is a highly prevalent inflammatory skin condition which is often resistant to conventional treatments. Molecular insights of CHE remain limited. Tape stripping combined with high-throughput RNA sequencing can now provide a better insight into CHE pathogenesis in a minimally invasive fashion.

View Article and Find Full Text PDF
Article Synopsis
  • Signal transduction is key for communication and response in microbial communities, allowing them to adapt to environmental changes and establish structures for collective behaviors.
  • Microbial communication occurs through methods like quorum sensing, biofilm formation, and chemotaxis, which help coordinate activities, enhance resource use, and improve resilience against stress.
  • Understanding these signaling processes, especially in synthetic microbial consortia, has important implications for biotechnology, including biosensors, biodegradation, and waste management.
View Article and Find Full Text PDF

Background: Surgical resection is the gold standard treatment for early-stage non-small cell lung cancer (NSCLC). Prior studies have found that delayed treatment carries risk of disease progression. However, factors that predict delay to surgery are relatively understudied.

View Article and Find Full Text PDF