Publications by authors named "E Dan Hershey"

Objective: We evaluate the safety of outpatient parotidectomy. We evaluate factors that lead to planned admission and compare costs. We evaluate trends toward outpatient, and the outcomes of switching admission status, total versus superficial approach, and ambulatory versus hospital site.

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Objectives: We sought to study the incidence of patient-initiated communication after parotidectomy, identify patient and surgical factors associated with patient-initiated communication, and evaluate trends and possible areas for improvement.

Methods: A retrospective cohort study of patients who underwent parotidectomy without combined procedures from 2018 to 2022 in a single tertiary-care institution was performed. We reviewed all patient communications documented within the electronic medical record within 30 days of discharge.

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Objective: Intralabyrinthine schwannomas (ILSs) are a rare cause of deafness. Patients with ILS confined to the semicircular canals and the vestibule (intravestibular schwannomas) are potential candidates for cochlear implantation for hearing rehabilitation, a new option for patients with unilateral hearing loss since the 2019 FDA approval of cochlear implant (CI) for single-sided deafness. In this report, we describe an evolving management approach for ILSs causing hearing loss.

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Article Synopsis
  • High-risk lesions (HRLs) in breast tissue are linked to an increased risk of breast cancer, particularly in patients with gene variants associated with breast cancer predisposition.
  • In a study of patients with germline pathogenic variants (PVs) and HRLs, the majority of lesions were atypical ductal hyperplasia (ADH) and lobular neoplasia (LN), with some patients showing low upgrade rates to malignancy following surgical excision.
  • Overall, patients without upgrades still had a notable 3-year breast cancer risk of 13.1%, mostly for estrogen receptor-positive (ER +) cancer, highlighting the need for potential surgical or preventive measures for those with HRLs and PVs.
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Background: ABT-751 is a novel orally available antimitotic agent that targets microtubule polymerization. This mechanism may suggest potential activity in canine lymphoma.

Objective: Determine a maximum tolerated dose for ABT-751, and assess long-term tolerability and activity in canine lymphoma.

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