Publications by authors named "E Daghofer"
Article Synopsis
- The study compares the effectiveness of two types of ELISA tests, an immunoblot (IB), and CXCL13 levels in diagnosing Neuroborreliosis (NB) in 27 adults and 23 children showing symptoms of the disease.
- Results indicated that the recombinant ELISA showed the highest sensitivity, identifying 58% of patients with definite NB, while the flagellum ELISA was the least sensitive, and only 26% of patients were consistently identified across all tests.
- The findings highlight the need for standardized testing methods to improve the accuracy of NB diagnoses, emphasizing the importance of using various tests, including IB and CXCL13 levels, for better diagnostic criteria.
Background: Diagnosis of Epstein-Barr virus (EBV) infection is routinely conducted by clinical laboratories, especially to diagnose infectious mononucleosis. At an estimated general population incidence of 1:200, this represents a potentially significant testing burden. We evaluated the reliability of the Siemens Novagnost® and Enzygnost® EBV microtiter assays measuring VCA IgM and IgG, and EBNA-1 IgG for clinical diagnosis of EBV-related infectious mononucleosis.
View Article and Find Full Text PDFObjectives: Diagnosis of Lyme neuroborreliosis (NB) depends on the proof of intrathecal antibody production against Borrelia burgdorferi. CXCL13 has been seen to be elevated early in NB, before antibody production has started. In this study, we determined the diagnostic role of the CXCL13 chemokine in cerebrospinal fluid (CSF) and serum for the first time in pediatric NB patients as well as in adults, compared to controls and blood donors (BD).
View Article and Find Full Text PDFBackground: In February 2009, a cluster of rubella cases was recognized in Austria occurring between calendar weeks 3 and 7, 2009 after a long period of low rubella virus activity. A nationwide 2-dose measles, mumps, and rubella vaccination program had been introduced in 1994 to prevent this childhood illness.
Methods: An epidemiologic investigation was conducted to describe the cluster by time, place, and person.
Since October 2008, a total of 143 cases of rubella have affected the two Austrian provinces Styria and Burgenland. The index case occurred in mid-October 2008, but was not notified to the public health authorities until February 2009, when the Austrian Agency for Health and Food Safety was asked to investigate a cluster of 32 rubella cases (24 laboratory-confirmed and eight clinically suspected cases). No case of rubella had been reported in the two affected provinces between February 2007 - when statutory notification for rubella was implemented - and mid-October 2008.
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