Publications by authors named "E D Nicol"

Background: Diabetes mellitus is an established cardiovascular risk factor. We assessed the impact of diabetes mellitus on quantitative plaque and long-term outcomes in patients with and without diabetes mellitus in the Scottish COmputed Tomography of the HEART (SCOT-HEART) trial.

Methods: Coronary artery calcium (CAC) was assessed on non-contrast computed tomography (CT).

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Rationale: Unrecognised coronary artery disease (CAD) may contribute to adverse outcomes in chronic obstructive pulmonary disease (COPD). Improved identification of at-risk groups could inform better preventative care. We aimed to evaluate the burden and relationships of radiologically detectable CAD in COPD, establish frequency of occult disease, and examine potential cardiovascular screening methods.

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Article Synopsis
  • Janus NanoRods (JNR) are unique colloids with two different chemical surfaces, making them tricky to create due to their tiny size and shape.
  • A new method for producing JNR leverages the self-assembly of specially designed polymers in water, resulting in nanocylinders that remain in a frozen state and rely heavily on the initial assembly conditions.
  • The study reveals that factors like the rate of water addition, the concentration of polymers, and temperature affect the size and form of the assembled structures, providing insights for tailoring these materials for specific applications.
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  • - Human threadworm is a globally distributed parasite affecting over 600 million people, with serious implications for immunosuppressed individuals, yet its prevalence among Fijian migrants in the UK is largely unknown.
  • - A study involving 250 Fijian migrants in the UK revealed a significant rate of gastrointestinal parasites (GIPs), with 35.1% testing positive for threadworm and 6.8% for hookworms, based on comprehensive diagnostic methods.
  • - Findings emphasized the need for specialized parasitological testing, particularly multiplex real-time PCR (rtPCR), which proved more effective than traditional microscopy in diagnosing infections among chronic cases in this population.
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