Publications by authors named "E D Heller"
Article Synopsis
- Noncoding RNA plays a crucial role in regulating the expression of specific genes.
- One of these genes is associated with behaviors influenced by drugs and stress.
- Understanding this relationship could lead to better insights into how these factors affect behavior. *
Quantum scars refer to eigenstates with enhanced probability density along unstable classical periodic orbits. First predicted 40 years ago, scars are special eigenstates that counterintuitively defy ergodicity in quantum systems whose classical counterpart is chaotic. Despite the importance and long history of scars, their direct visualization in quantum systems remains an open field.
View Article and Find Full Text PDFWhen short plasma half-life drugs act only briefly, they require frequent or continuous administration. We report the engineering of a non-invasive oral drug delivery system for long-term, continuous administration of these drugs. Their non-invasive, long-term, continuous administration at daily doses exceeding 100 mg has, for many years, been considered an insurmountable challenge.
View Article and Find Full Text PDFThe intricate relationship between electrons and the crystal lattice is a linchpin in condensed matter, traditionally described by the Fröhlich model encompassing the lowest-order lattice-electron coupling. Recently developed quantum acoustics, emphasizing the wave nature of lattice vibrations, has enabled the exploration of previously uncharted territories of electron-lattice interaction not accessible with conventional tools such as perturbation theory. In this context, our agenda here is two-fold.
View Article and Find Full Text PDFArticle Synopsis
- - Chronic stress plays a significant role in mood and anxiety disorders, and previous studies suggest that vitamin B12 may help improve resilience against stress and depression, although the mechanisms behind this connection are still unclear.
- - Researchers used a mouse model to explore how vitamin B12 affects gene expression related to stress resilience, discovering that Ttr (transthyretin) is a key target for vitamin B12 and is linked to depression-like behaviors.
- - The study found that vitamin B12 reduces DNA methylation in the Ttr promoter, providing a causal link between vitamin B12, Ttr, and stress-related behaviors, which suggests that dietary interventions could be beneficial for mood disorders.