Publications by authors named "E D Grober"
Article Synopsis
- A decline in episodic memory is an early sign of Alzheimer’s disease and is important in evaluating treatment effectiveness in clinical trials, particularly through various memory tests.
- This study aimed to assess the correlation between different episodic memory tests and plasma biomarkers related to Alzheimer’s, examining data from 161 cognitively normal older adults.
- Results indicated that the Free and Cued Selective Reminding Test with Immediate Recall was more sensitive to changes in cognitive function linked to certain plasma biomarkers compared to other tests, highlighting the importance of using specific memory assessments in Alzheimer’s research.
Introduction: During vasectomy reversal (VR), accurate intraoperative microscopic assessment of the vasal fluid for sperm presence and quality is essential in determining the indication for a vasovasostomy (VV) or vasoepididymostomy (VE). The use of testosterone therapy (TT), known to supress spermatogenesis, can potentially interfere with this determination. This initiative evaluated the impact of TT on vasal and epididymal fluid sperm characteristics and intraoperative decision-making among men on TT at the time of VR.
View Article and Find Full Text PDFIdiopathic secondary azoospermia occurrence in men with oligospermia over time.
J Assist Reprod Genet
August 2024
Article Synopsis
- The study focused on how men with oligospermia (low sperm count) might develop idiopathic secondary azoospermia (ISA) over time, looking for risk factors in a group of 1,056 patients.
- Results showed that men with extremely severe oligospermia (≤1 M/ml) had a significantly higher chance (21.1% after 3-5 years) of developing ISA compared to those with severe (4.8%) and mild oligospermia (0%).
- The findings emphasize the need for sperm banking in men with extremely low sperm counts and low testosterone levels, as they are at a higher risk of becoming azoospermic, while those with >1 M/ml are less
Background: Paternal age association with sperm parameters has been previously studied, demonstrating a decrease in semen volume, sperm motility, and sperm morphology, but not in sperm concentration. However, scarce data exists on the individual intra-personal changes in semen parameters with time.
Study Design: Retrospective cohort study.