Publications by authors named "E D Dodson"
Giant cell tumor of bone (GCTB) is a rare bone tumor often necessitating surgical intervention, radiation therapy, or treatment with bisphosphonates or denosumab. Tc-MDP bone scintigraphy for GCTB has limited specificity, and the relatively high uptake of F-FDG in GCTB makes it challenging to differentiate it from other benign bone tumors. More specific detection and treatment modalities for GCTB are needed to enhance patient monitoring and outcomes.
View Article and Find Full Text PDFArticle Synopsis
- Researchers developed a new method to synthesize 9 core-functionalised naphthalene diimide (c-NDI) compounds using a three-step, solvent-free process that activates chemicals mechanically.
- They achieved selective dibromination of naphthalenetetracarboxylic dianhydride in a vibratory ball mill, producing a key intermediate (2,6-dibromonaphthalenediimide) quickly and efficiently within 5 hours, significantly faster than traditional methods.
- The study also successfully executed rapid Heck-type cross coupling reactions with various styrene residues, resulting in good yields of c-NDIs without the need for extra heating or solvents, making the process robust against environmental conditions.
Leflunomide-Associated Wound Complication After Cochlear Implantation: A Case Report.
Ann Otol Rhinol Laryngol
October 2024
Introduction: Cochlear implantation has become an increasingly common strategy for aural rehabilitation in patients with severe to profound hearing loss who no longer benefit from conventional amplification. In conjunction, immunosuppressive therapies (e.g.
View Article and Find Full Text PDFIn Escherichia coli and Salmonella typhimurium, cysteine biosynthesis requires the products of 20 or more cys genes co-ordinately regulated by CysB. Under conditions of sulphur limitation and in the presence of the inducer, N-acetylserine, CysB binds to cys promoters and activates the transcription of the downstream coding sequences. CysB is a homotetramer, comprising an N-terminal DNA binding domain (DBD) and a C-terminal effector binding domain (EBD).
View Article and Find Full Text PDFBackground: Surgical repair is recommended for the treatment of high-grade partial and full thickness rotator cuff tears, although evidence shows surgery is not necessarily superior to non-surgical therapy. The purpose of this study was to compare percutaneous orthobiologic treatment to a home exercise therapy program for supraspinatus tears.
Methods: In this randomized-controlled, crossover design, participants with a torn supraspinatus tendon received either 'BMC treatment', consisting of a combination of autologous bone marrow concentrate (BMC) and platelet products, or underwent a home exercise therapy program.