Disease Course and Treatment Outcomes in Patients With De Novo Small-Cell Lung Cancer and Epidermal Growth Factor Receptor Exon 20 Insertion: Two Case Reports.

We report the first two cases of EGFR exon20ins SCLC, treated with amivantamab and TKIs.

Debridement, antibiotics and implant retention for prosthetic joint infection: comparison of outcomes between total hip arthroplasty and hip resurfacing.

Introduction: The management of prosthetic joint infection (PJI) has been widely studied in the context of total hip arthroplasty (THA). However, the outcomes of debridement, antibiotics and implant retention (DAIR) for PJI have never been compared between hip resurfacing arthroplasty (HRA) and THA. This led us to carry out a retrospective case-control study comparing the surgical treatment of post-operative infections between HRA and THA to determine the infection remission rate and the medium-term functional outcomes.

Mixed Matrix Poly(Vinyl Alcohol)-Copper Nanofibrous Anti-Microbial Air-Microfilters.

Membranes decorated with biocide materials have shown great potential for air sanitization but can suffer from biocide agent leaching by dissolution in water. In order to tackle the diffusion of biocide metal ions from the fiber matrix, composite nanofiber membranes of poly(vinyl alcohol) (PVA) cross-linked with copper (II) acetate have been successfully engineered via sol-gel electrospinning, providing a stable mean for air bactericidal microfiltration. The novelty lies in the bonding strength and homogeneous distribution of the fiber surface biocide, where biocide metals are incorporated as a sol within a polymer matrix.