Publications by authors named "E D'Adamo"
Article Synopsis
- In utero exposure to maternal conditions like obesity and Gestational Diabetes Mellitus (GDM) can negatively impact newborns through changes in DNA methylation patterns.
- The study examined 101 Caucasian mother-infant pairs, finding that lower DNA methylation levels in newborns from GDM mothers were linked to lower birth weight and size.
- Additionally, higher DNA methylation levels on the fetal side of the placenta were observed in obese mothers, correlating with increased maternal cholesterol levels, further influencing the metabolic health of the children.
Breast milk is the natural source of nutrition for infants, but while it supports their health, it can also be a potential source of toxic inorganic particulate matter, and this applies to both breast milk and industrially produced milk. The aim of the present study was to evaluate the presence of nanoparticles in both breast milk and formula milk samples. We collected and analyzed, via a new electron scanning microscopic procedure, 19 samples of breast milk from Italian women and 19 formula milk samples produced by different companies.
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- - The study examines how factors like gestational age, birth weight, delivery mode, and gender influence the measurement of blood pH and gas analytes (BPGA) in newborns, particularly healthy preterm and term infants.
- - Results indicate that preterm infants have significantly different BPGA levels compared to term infants, influenced by their delivery mode and gender, particularly in terms of carbon dioxide levels and hemoglobin types.
- - The findings suggest that BPGA measurements could be unreliable due to these perinatal characteristics, highlighting the need for further research to establish reliable reference values for different newborn populations.
Breast milk (BM) is a unique food due to its nutritional composition and anti-inflammatory characteristics. Evidence has emerged on the role of Presepsin (PSEP) as a reliable marker of early sepsis diagnosis. In the present study, we aimed to investigate the measurability of PSEP in BM according to different maturation stages (colostrum, C; transition, Tr; and mature milks, Mt) and corrected for delivery mode and gender.
View Article and Find Full Text PDFObjectives: Early sepsis detection and diagnosis still constitutes an open issue since the accuracy of standard-of care parameters is biased by a series of perinatal factors including hypoxia. Therefore, we aimed at investigating the effect of fetal chronic hypoxia insult on urine levels of a promising new marker of sepsis, namely presepsin (P-SEP).
Methods: We conducted a prospective case-control study in 22 cases of early-intrauterine growth restriction (E-IUGR) compared with 22 small-for-gestational-age (SGA) newborns and 66 healthy controls.