[Hyperhomocysteinemia complicated by myocardial infarction and portal vein thrombosis--case report].

Hyperhomocysteinemia (HHcy) can be associated with deficiency of group B vitamins and folic acid. HHcy might also results from renal insufficiency, diabetes, hypothyreosis or malignant diseases. In same cases HHcy is connected with mutations of genes involved in its metabolism.

[Hemostatic disturbances in obesity].

Overweight and obesity belong to the group of chronic diseases in which there is a substantially increased risk of thromboembolic incidents. The changes involve both arterial and venous system. The decisive role in their development seems to have disorders ofhemostasis including both excessive activation of coagulation system and/or inhibition of fibrinolysis.

Association between sensitization to Aureobasidium pullulans (Pullularia sp) and severity of asthma.

Background: Recent data indicate that fungi may contribute to increased severity of asthma.

Objectives: To determine the prevalence of allergy to 15 mold allergens among patients hospitalized because of exacerbation of asthma and to evaluate the relationship between the severity of the disease and allergy to particular molds.

Methods: Skin prick tests with standard aeroallergens of airborne allergens, including grass, tree, Dermatophagoides pteronyssinus, Dermatophagoides farinae, feather, and cat and dog fur, and a panel of mold allergens, including Alternaria, Cladosporium, Aspergillus, Penicillium, Trichothecium, Chaetomium globosum, Epicoccum, Epidermophyton, Helminthosporium, Aureobasidium pullulans, Rhizopus nigricans, Fusarium, Mucor, Merulius lacrymans, and yeast mix, were performed in 105 asthmatic patients and 30 controls.

[Negative D-dimers and exclusion of venous thromboembolism--own experience].

The assessment of D-dimer concentration has become essential step during diagnostic algorithm of venous thromboembolism (VTE). This test characterizes high sensitivity but limited specificity. Negative D-dimer with high probability excludes VTE.