Prognostic impact of circulating tumor DNA detection in portal and peripheral blood in resected pancreatic ductal adenocarcinoma patients.

In PDAC patients, ctDNA detection's prognostic significance needs validation especially in resected patients. This study investigated ctDNA kinetics in portal and peripheral blood before and after resection, and whether tissue mobilization during surgery influences ctDNA detection. In this single-center prospective cohort, portal and peripheral blood were drawn during pancreaticoduodenectomy before and after tissue mobilization, during 12 postoperative months and were associated with overall survival (OS), recurrence-free survival (RFS) and CA19-9 (secondary endpoints).

Factors associated with gingival recession prevalence in undergraduate students of the Faculty of Dentistry of the Universidad de los Andes in the year 2022.

Objective: To determine the prevalence of gingival recessions in students of the faculty of odontology at Universidad de Los Andes and the factor associated with its presence.

Methods: In this cross-sectional study, a randomized stratified sampling was used to select the students. The sample included 311 undergraduate students evaluated between March and December 2022.

Curative surgical treatment of common bile duct stones: Retrospective cohort study.

Background: In the event of symptomatic common bile duct (CBD) stones with dilated CBD, one possible curative treatment option is stone extraction through choledocotomy associated with cholecystectomy. Endoscopic treatment is only reserved for residual stones at 6 weeks. The aim of this study was to evaluate the results from laparoscopic curative surgical treatment of CBD stones with dilated CBD.

1,2-Azolylamidino ruthenium(II) complexes with DMSO ligands: electro- and photocatalysts for CO reduction.

New 1,2-azolylamidino complexes -[RuCl(DMSO)(NHC(R)az*-κN,N)]OTf [R = Me (2), Ph (3); az* = pz (pyrazolyl, a), indz (indazolyl, b)] are synthesized chloride abstraction from their corresponding precursors ,-[RuCl(DMSO)(az*H)] (1) after subsequent base-catalyzed coupling of the appropriate nitrile with the 1,2-azole previously coordinated. All the compounds are characterized by H NMR, C NMR and IR spectroscopy. Those derived from MeCN are also characterized by X-ray diffraction.