Publications by authors named "E Cubukcu"
Background: Immune checkpoint inhibitors (ICI) are generally associated with rare cardiac side effects, yet instances like myocarditis can be fatal. Therefore, detecting and managing left ventricular dysfunction early in ICI therapy is vital.
Objectives: This study aims to evaluate whether left ventricular global longitudinal strain (LV GLS) is a predictor for early detection of cardiac dysfunction in patients receving ICI.
Article Synopsis
- * Among 106 patients, 83 had CN, and those who had the surgery could continue their nivolumab treatment for longer (14.5 months) compared to those who didn't have the surgery (6.7 months).
- * Overall survival was better for patients with CN (22.9 months) compared to those without it (8.1 months), but the surgery and certain medical scores were important factors for how long they lived.
Article Synopsis
- * This study analyzed the effectiveness of two treatments, pazopanib and sunitinib, in non-ccRCC patients across 22 hospitals, looking at progression-free survival, overall survival, and patient response rates.
- * The findings suggest that pazopanib and sunitinib have similar efficacy, with specific patient characteristics affecting outcomes; pazopanib could be considered a viable treatment option alongside sunitinib and cabozantinib.
Purpose: To report a case of Vogt-Koyanagi-Harada (VKH)-like uveitis under treatment with Dabrafenib and Trametinib for metastatic malignant melanoma, representing the longest follow-up (49 months) with retinal multimodal imaging.
Methods: Retrospective case report.
Results: A 49-year-old female with metastatic relapsing cutaneous malignant melanoma presented with blurry vision in both eyes for 1 week.
To evaluate radiological and clinical features in metastatic anaplastic lymphoma kinase+ non-small cell lung cancer patients and crizotinib efficacy in different lines. This national, non-interventional, multicenter, retrospective archive screening study evaluated demographic, clinical, and radiological imaging features, and treatment approaches in patients treated between 2013-2017. Totally 367 patients (54.
View Article and Find Full Text PDF