Publications by authors named "E Cruz-Iglesias"
Recommendations for the study of monoclonal gammopathies in the clinical laboratory. A consensus of the Spanish Society of Laboratory Medicine and the Spanish Society of Hematology and Hemotherapy. Part I: Update on laboratory tests for the study of monoclonal gammopathies.
Clin Chem Lab Med
November 2023
Article Synopsis
- Monoclonal gammopathies (MG) involve the growth of plasma cells that create abnormal immunoglobulins known as monoclonal protein (M-protein), which are important for clinical management.
- A systematic review examined various laboratory tests for detecting M-protein in serum and urine, along with essential biochemistry and hematology assessments, covering studies published from 2009 to 2022.
- The paper outlines different diagnostic methods like electrophoresis and mass spectrometry, their limitations, and their roles in diagnosing, monitoring, and evaluating treatment responses in MG.
White blood cell count: a valuable tool for suspecting Cushing's syndrome.
J Endocrinol Invest
January 2023
Purpose: Simple screening tests to determine whether Cushing's syndrome (CS) should be ruled out are lacking. Tools that enable early diagnosis could reduce morbidity and associated sequelae. The potential of glucocorticoid-induced changes in the white blood cell (WBC) count for raising suspicion of CS is assessed.
View Article and Find Full Text PDFBackground: Monoclonal protein (M-protein) concentrations are measured by serum protein electrophoresis (SPE). Two methods are used for demarcating the M-protein area in the electropherogram: perpendicular drop (PD) and tangent skimming (TS). The aim of this study was tocompare both methods and to establish which is the most accurate and precise.
View Article and Find Full Text PDFIntroduction: The 2013 Kidney Disease Outcomes Quality Initiative Clinical Practice Guideline suggests measuring cystatin C (sCys) in adults with glomerular filtration rate (GFR) based on creatinine (sCr) between 45 and 59 mL/min/1.73 m if confirmation of chronic kidney disease (CKD) is required. There is not enough evidence to recommend the use of sCys or sCr to estimate GFR in kidney transplant recipients.
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