In Situ Monitoring of Mechanofluorescence in Polymeric Nanofibers.

Mechanofluorescent polymers represent a promising class of materials exhibiting fluorescence changes in response to mechanical stimuli. One approach to fabricating these polymers involves incorporating aggregachromic dyes, whose emission properties are governed by the intermolecular distance, which can, in turn, be readily altered by microstructural changes in the surrounding polymer matrix during mechanical deformation. In this study, a mechanofluorescent additive featuring excimer-forming oligo(p-phenylene vinylene) dyes (tOPV) is incorporated into electrospun polyurethane fibers, producing mats of fibers with diameters ranging from 300 to 700 nm.

Biomechanical characterization of the passive porcine stomach.

The complex mechanics of the gastric wall facilitates the main digestive tasks of the stomach. However, the interplay between the mechanical properties of the stomach, its microstructure, and its vital functions is not yet fully understood. Importantly, the pig animal model is widely used in biomedical research for preliminary or ethically prohibited studies of the human digestion system.

Mechanobiological considerations in colorectal stapling: Implications for technology development.

Technological advancements in minimally invasive surgery have led to significant improvements in patient outcomes. One such technology is surgical stapling, which has evolved into a key component of many operating rooms by facilitating ease and efficacy in resection and repair of diseased or otherwise compromised tissue. Despite such advancements, adverse post-operative outcomes such as anastomotic leak remain a persistent problem in surgical stapling and its correlates (i.

Electrophysiological and neuropsychological assessment of cognition in spinocerebellar ataxia type 1 patients: a pilot study.

Background: Event-related potentials (ERPs) reflect cognitive processing: negative early components (N100, N200) are involved in the sensory and perceptual processing of a stimulus, whereas late positive component P300 requires conscious attention. Both neuropsychological and affective disorders are present in patients with spinocerebellar ataxia type 1 (SCA1), but the underlying mechanisms need further clarification.

Materials And Methods: In this pilot study, we assessed cognitive processing by recording auditory ERPs in 16 consecutive SCA1 patients and 16 healthy controls (HC) matched for age and sex.

Exploring Information Flow from Posteromedial Cortex during Visuospatial Working Memory: A Magnetoencephalography Study.

The posteromedial cortex (PMC) is a major hub of the brain's default mode network, and is implicated in a broad range of internally driven cognitions, including visuospatial working memory. However, its precise contribution to these cognitive processes remains unclear. Using MEG, we measured PMC activity in healthy human participants (young adults of both sexes) while they performed a visuospatial working memory task.