Publications by authors named "E Colin-Ramirez"
Background: SODIUM-HF was a large clinical trial testing dietary sodium restriction compared to usual care in patients with heart failure that showed no reduction in clinical events. It has been suggested that diuretic doses in response to dietary sodium modification may have influenced the trial results.
Objective: We assessed the effects of baseline diuretic dose and diuretic dose changes on clinical outcomes in the SODIUM-HF trial.
Knowledge, Attitudes, and Behaviors Toward Salt Consumption and Its Association With 24-Hour Urinary Sodium and Potassium Excretion in Adults Living in Mexico City: Cross-Sectional Study.
Interact J Med Res
November 2024
Article Synopsis
- The World Health Organization advises that adults should consume less than 2000 mg of sodium daily, but the Mexican population, similar to many around the world, exceeds this recommendation and often lacks adequate potassium intake.
- This study aims to assess the knowledge, attitudes, and behaviors (KAB) related to sodium intake among a Mexican population and to investigate how these factors correlate with actual sodium and potassium excretion through urinary tests.
- Results showed that 232 participants (mainly women) had high urinary sodium levels (2582.5 mg/day) and inadequate potassium levels (1493.5 mg/day), with a notable difference in the awareness of sodium consumption between genders, as more men were unaware of their sodium intake compared to women
Article Synopsis
- - This analysis of the SODIUM-HF study examined how dietary sodium intake affects cardiovascular health in heart failure patients over two years, focusing on hospitalizations and death rates.
- - Among 792 participants, most consumed between 1501-3000 mg/day of sodium, and no significant connection was found between sodium intake levels or changes and health outcomes at 12 or 24 months.
- - However, those who reduced their sodium intake to below 1500 mg/day at 6 months showed a trend towards lower risks of cardiovascular issues, indicating a potential benefit that needs further research.
Background: In heart failure (HF) trials, there has been an emphasis on utilizing more patient-centered outcomes, including quality of life (QoL) and days alive and out of hospital. We aimed to explore the impact of QoL adjusted days alive and out of hospital as an outcome in 2 HF clinical trials.
Methods: Using data from 2 trials in HF (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure [GUIDE-IT] and Study of Dietary Intervention under 100 mmol in Heart Failure [SODIUM-HF]), we determined treatment differences using percentage days alive and out of hospital (%DAOH) adjusted for QoL at 18 months as the primary outcome.
Dietary fibers are associated with favorable gastrointestinal, immune, and metabolic health outcomes when consumed at sufficient levels. Despite the well-described benefits of dietary fibers, children and adolescents continue to fall short of daily recommended levels. This gap in fiber intake (i.
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