Publications by authors named "E Clara"

Article Synopsis
  • Obstructive sleep apnea (OSA) is common and requires accurate diagnosis; this study compares the effectiveness of in-person vs. video instructions for type III sleep studies.
  • One hundred patients were divided into two groups, receiving either face-to-face or video instructions, and the technical quality of their sleep studies was evaluated.
  • Results showed that while both instruction methods produced valid studies, the video group had better oximetry signal quality, making it a viable option for OSA diagnosis without increasing errors.
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Article Synopsis
  • This study assesses the potential of using coal ash in asphalt mixes by examining its physical and chemical properties using various analytical techniques like SEM and XRD.
  • The research compares asphalt mixes made with coal ash to traditional gneissic aggregates, focusing on their compaction, water resistance, and rutting performance.
  • Findings suggest that coal ash can be technically feasible for use in asphalt formulations, despite exhibiting inert and hydrophilic properties similar to gneissic fillers.
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The most frequent genetic alteration in acute myeloid leukemia (AML) is the mutation of nucleophosmin 1 (NPM1). Yet, its downstream oncogenic routes are not fully understood. Here, we report the identification of one long noncoding RNA (lncRNA) overexpressed in NPM1-mutated AML patients (named LONA) whose intracellular localization inversely reflects that of NPM1.

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Developmental genes contribute to cancer, as reported for the homeobox gene playing a tumor suppressor role in the gut. In this study, we show that human colon cancers exhibiting the highest reduction in expression belong to the serrated subtype with the worst evolution. In mice, mosaic knockout of in the adult intestinal epithelium induces the formation of imperfect gastric-type metaplastic lesions.

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Long non-coding RNAs are defined as transcripts larger than 200 nucleotides but without protein-coding potential. There is growing evidence of the important role of long non-coding RNAs in cancer initiation, development and progression. In this study, we sought to evaluate the long non-coding RNA expression profile of patients with cytogenetically normal acute myeloid leukemia (AML).

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