Publications by authors named "E Ciociola"
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global epidemic. MASLD has a strong genetic component, and a common missense variant (rs2642438) in the mitochondrial amidoxime-reducing component 1 (MARC1) gene confers protection against its onset and severity. However, there are contrasting results regarding the mechanisms entangling this protection.
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- The study aimed to analyze treatment patterns for childhood glaucoma in the U.S. by examining patient records from 2013 to 2020.
- It included 3069 patients, revealing that only 16.1% underwent surgery while 93.6% were treated with medications, with specific procedures varying based on the type of glaucoma.
- Key factors influencing the need for surgeries included having primary congenital glaucoma, higher intraocular pressure, and being younger than one year at diagnosis.
Background: New drugs to target different pathways in pulmonary hypertension has resulted in increased combination therapy, but details of this use in infants are not well described. In this large multicenter database study, we describe the pharmacoepidemiology of combination pulmonary vasodilator therapy in critically ill infants.
Methods: We identified inborn infants discharged home from a Pediatrix neonatal ICU from 1997 to 2020 exposed to inhaled nitric oxide, sildenafil, epoprostenol, or bosentan for greater than two consecutive days.
Objective: Characteristics of individuals with angle closure may be useful in targeted screening of family members. Here, we assess if findings gathered during examination and imaging of patients with a known angle-closure diagnosis (probands) could better determine the risk of angle closure in the patients' siblings.
Design: Cross-sectional study of patients with known angle closure and their siblings.
Article Synopsis
- * Found that Black and Hispanic patients experienced worse vision outcomes like CDR progression and poor vision compared to non-Hispanic White patients, with Hispanics also having higher rates of low vision diagnoses.
- * Noted that Black and Hispanic patients were less likely to access eye care services like exams and OCTs, despite Black patients having more frequent inpatient encounters.