Publications by authors named "E Cierpka"
Equine dendritic cells (eqDC) can be generated from peripheral blood monocytes by propagation in GM-CSF and IL-4. Despite similarities with the generation of human DC, we found significant improvements for eqDC generation and functional influences on eqDC maturation. The fractionation of peripheral blood mononuclear cells (PBMC) by two subsequent gradients at densities of 1.
View Article and Find Full Text PDFDendritic cell (DC) maturation can occur by different types of stimuli. Previously, we described that murine DC matured with tumor necrosis factor (TNF) up-regulate surface MHC and costimulatory molecules but lack cytokine release, and therefore termed them semi-mature DC. These TNF/DC-induced tolerance after intravenous (i.
View Article and Find Full Text PDFArticle Synopsis
- Researchers examined 41 workers involved in chlorfenvinphos production for liver damage, measuring various serum components and enzyme activities over two assessments 9 years apart.
- The first study indicated lower protein levels, with higher bilirubin and enzyme activities (ALT, AST, MDH), suggesting some liver impairment.
- The follow-up study generally confirmed these findings, showing continued low enzyme activity (ChE, AP) and increased ALT, reinforcing the evidence of slight liver damage.