Publications by authors named "E Chiconelli Faria"
We have studied repositioning of carvedilol (an antihypertensive drug) incorporated into MCM-41 mesoporous silica. The repositioning proposes a reduction in the slow pace of discovery of new drugs, as well as toxicological safety and a significant reduction in high research costs, making it an attractive strategy for researchers and large pharmaceutical companies. We obtained MCM-41 bysynthesis and functionalized it by post-synthesis grafting with aminopropyltriethoxysilane (APTES) only or with folic acid (FA), which gave MCM-41-APTES and MCM-41-APTES-FA, respectively.
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- Piedras are small nodules found on hair shafts, with white piedra previously linked to Trichosporon beigelii, now causing a reassessment of its causative agents.
- The first recorded case of white piedra was identified as being caused by Cutaneotrichosporon debeurmannianum, which was studied using scanning electron microscopy and cultures from Sabouraud medium.
- Genetic analysis showed 99.6% similarity between the nucleotide sequences of the isolated fungus and the 28S large ribosomal unit rDNA, confirming Cutaneotrichosporon debeurmannianum as the causative agent of this white piedra case.
Background: Little is known about the ultrastructure of Piedraia hortae.
Objective: To examine a P. hortae colony with scanning electron microscopy and investigate possible contributions to its the pathogenesis of black piedra.
We aimed to characterise vaccine-induced protection against COVID-19 during five waves caused by Variants of Concern (VOCs). This is a nested case-control study of 3,972 HCW primarily vaccinated with CoronaVac (98%) that evaluated symptomatic SARS-CoV-2 breakthrough infections (BI) in almost two-years follow-up until the 3rd Omicron wave. Predictors of protection against SARS-CoV-2 BI were analysed using conditional logistic regression models.
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