Publications by authors named "E Chazelle"

Background: The prevalence of syphilis, Chlamydia trachomatis (CT), and Neisseria gonorrhoeae (NG) in men who have sex with men (MSM) is very high. As these bacterial sexually transmitted infections (bSTIs) are frequently asymptomatic, they are often undiagnosed and therefore untreated. We aimed to characterize the profile of MSM who reported bSTI screening and diagnosis in the previous 12 months, and to identify the factors associated with a diagnosis of a bSTI among MSM in France.

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Article Synopsis
  • Since 2022, Europe has identified 4 cases of extensively drug-resistant Neisseria gonorrhoeae, particularly sequence type 16406, which is resistant to ceftriaxone and has high resistance to azithromycin.
  • In 2023, two new related cases were reported in France that share genetic links with the previous European cases and strains from Cambodia.
  • This highlights growing concerns about the spread of drug-resistant gonorrhea in Europe and its potential global implications.
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Article Synopsis
  • - During summer 2023, Europe saw a small uptick in mpox cases after a major outbreak in 2022, marked by peaks happening at different times in various countries!* - The demographic makeup of the new cases was similar to those from previous reports, maintaining the same trends.
  • - All collected case sequences from this recent resurgence belonged to clade IIb, highlighting the need for ongoing control efforts to eliminate mpox in the region.
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BackgroundDuring the 2022 mpox outbreak in Europe, primarily affecting men who have sex with men, a limited number of cases among children and adolescents were identified. Paediatric cases from outbreaks in endemic countries have been associated with a higher likelihood of severe illness. Detailed clinical case descriptions and interventions in school settings before 2022 are limited.

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Objectives: The aim was to estimate the effect of reported history of smallpox vaccination prior to 1980 on clinical expression of mpox.

Methods: We included all confirmed mpox cases identified by the national mpox surveillance system in France between May and July 2022. Cases tested positive for monkeypox virus or orthopoxviruses by PCR.

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