Conducting polymer functionalization in search of advanced materials in ionometry: ion-selective electrodes and optodes.

Functionalized conducting polymers (FCPs) have recently garnered attention as ion-selective sensor materials, surpassing their intrinsic counterparts due to synergistic effects that lead to enhanced electrochemical and analytical parameters. Following a brief introduction of the fundamental concepts, this article provides a comprehensive review of the recent developments in the application of FCPs in ion-selective electrodes (ISEs) and ion-selective optodes (ISOs), particularly as ion-to-electron transducers, optical transducers, and ion-selective membranes. Utilizing FCPs in these devices offers a promising avenue for detecting and measuring ions in various applications, regardless of the sample nature and composition.

Electroencephalographic Measures of Delirium in the Perioperative Setting: A Systematic Review.

Postoperative delirium (POD) is frequent in older adults and is associated with adverse cognitive and functional outcomes. In the last several decades, there has been an increased interest in exploring tools that easily allow the early recognition of patients at risk of developing POD. The electroencephalogram (EEG) is a widely available tool used to understand delirium pathophysiology, and its use in the perioperative setting has grown exponentially, particularly to predict and detect POD.

Tissue explants as tools for studying the epigenetic modulation of the GH-IGF-I axis in farmed fish.

Somatic growth in vertebrates is mainly controlled by the growth hormone (GH)/insulin-like growth factor I (IGF-I) axis. The role of epigenetic mechanisms in regulating this axis in fish is far from being understood. This work aimed to optimize and evaluate the use of short-term culture of pituitary and liver explants from a farmed fish, the gilthead seabream , for studying epigenetic mechanisms involved in GH/IGF-I axis regulation.

When "virtual" works and when it doesn't: A survey of physician and patient experiences with virtual care during the COVID-19 pandemic.

Objective: To assess the experience of virtual care among both patients and physicians across a range of clinical scenarios during the COVID-19 pandemic.

Methods: A web-based survey was disseminated to patients and physicians through a variety of media and healthcare communications from May 2020 to July 2021. Demographic details and attitudes across a range of virtual care domains were collected.