Publications by authors named "E Chabrun"
Background And Aims: We aimed to evaluate the feasibility, safety and efficacy of endoscopic submucosal dissection for recurrent rectal neoplastic lesions after transanal microsurgery of superficial rectal neoplasms.
Methods: Multicenter retrospective study.
Main Outcomes: recurrence at first endoscopic follow-up, En bloc, R0 and curative resections.
Introduction: The adoption of colorectal endoscopic submucosal dissection (ESD) is still limited in the West. A recent randomized trial showed that ESD is more effective and only slightly riskier than piecemeal endoscopic mucosal resection; reproducibility outside expert centers was questioned. We evaluated the results according to the annual case volume in a multicentric prospective cohort.
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- Missed lesions during colonoscopy can lead to post-procedure colorectal cancer, prompting the development of contrast-enhanced technologies like linked color imaging (LCI) for better polyp detection.
- A national, randomized trial compared polyp detection rates between standard white-light imaging (WLI) and LCI in the right colon, involving 764 patients across 10 endoscopy units.
- Results showed no significant difference in the proximal adenoma miss rate or miss rates for other types of lesions between the WLI-first and LCI-first groups, challenging the idea that LCI improves detection in routine colonoscopy.
Article Synopsis
- Achalasia is effectively treated with peroral endoscopic myotomy (POEM), but factors that contribute to early failure in treatment need further investigation, particularly in European populations.
- A retrospective study of 746 patients revealed an early failure rate of 9.4%, with significant predictors including age ≤45 years, achalasia types I and III, and severe adverse events during the procedure.
- The study highlighted that a high Eckardt score before the procedure is also a key factor, emphasizing the need to monitor retrosternal pain levels post-operation for better outcomes.
Article Synopsis
- The study aimed to compare long-term outcomes for patients with high-risk T1 colorectal cancer who underwent endoscopic resection, assessing the effectiveness of additional surgery versus surveillance alone.
- Data was collected from patients treated at 14 centers between 2012 and 2019, with the primary outcome focusing on cancer recurrence or death within 48 months.
- Results showed no significant difference in the rates of death or cancer recurrence between the two groups, suggesting that additional surgery may not provide benefits for these patients.