Publications by authors named "E Chabrillac"
Introduction: Salivary carcinomas of the tongue represent a therapeutic challenge as their radical excision is particularly mutilating. We aimed to study the oncologic and functional outcomes of advanced stages salivary carcinomas of the tongue.
Materials And Methods: This retrospective multicentric study, based on the French national network on rare head and neck cancers (REFCOR), included all patients with a T3-T4 salivary carcinoma of the tongue, diagnosed between January 2009 and December 2018.
Article Synopsis
- Salivary carcinomas of minor salivary glands, particularly in the tongue, are rare tumors that may require surgery and/or (chemo-)radiotherapy for treatment.
- A study involving 103 patients diagnosed between 2009 and 2018 found that the most common types were adenoid cystic and mucoepidermoid carcinomas, with surgery being the primary treatment for most cases.
- Results indicated that 5-year overall survival was 84.7%, while event-free survival was lower at 38.6%; nonsurgical treatment, alcohol use, and tumor location negatively impacted event-free survival, while nodal positivity was a key factor affecting overall survival.
Objective: To elucidate the prognostic implications of mucosal and deep margin distances in oral tongue squamous cell carcinoma (OTSCC), and to assess a different margin cut-off value in T1-T2 versus T3-T4 tumors.
Methods: This single-center retrospective study included 223 patients who received surgery for a primary OTSCC between January 2017 and December 2021.
Results: Multivariable analysis showed that deep margin distance ≥3 mm in T1-T2 tumors and ≥5 mm in T3-T4 tumors was significantly associated with better RFS and OS.
Purpose: Substantial changes have been made in the neck management of patients with head and neck squamous cell carcinomas (HNSCC) in the past century. These have been fostered by changes in cancer epidemiology and technological progress in imaging, surgery, or radiotherapy, as well as disruptive concepts in oncology. We aimed to review changes in nodal management, with a focus on HNSCC patients with nodal involvement (cN+) undergoing (chemo)radiotherapy.
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