Publications by authors named "E Ceccarelli"

Article Synopsis
  • Type 2 diabetes mellitus (T2DM) is a common metabolic disorder that significantly contributes to cardiovascular complications and healthcare costs globally.
  • A 12-month study on 65 Caucasian T2DM patients evaluated the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) like dulaglutide and semaglutide on cardio-metabolic health, with 54 participants completing the trial.
  • Results showed GLP-1RAs improved several cardiovascular risk factors, including weight loss, reduced visceral fat, lower LDL cholesterol and triglycerides, increased adiponectin levels, and improvements in kidney function and arterial health.
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In this study, we employ a comprehensive approach to model the concurrent effects of the COVID-19 epidemic and heatwaves on all-cause excess mortality. Our investigation uncovers distinct peaks in excess mortality, notably among individuals aged 80 years and older, revealing a strong positive correlation with excess temperatures (ET) during the summer of 2022 in Italy. Furthermore, we identify a notable role played by COVID-19 hospitalizations, exhibiting regional disparities, particularly during the winter months.

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: Endometriosis is a female chronic inflammatory disease in which endometrial tissue develops outside the uterine cavity. It is a complex pathology, which significantly contributes to morbidity in premenopausal women, leading to chronic pain, infertility, and subfertility negatively impacting physical and emotional well-being and the overall quality of life. The public health burden of endometriosis remains elusive and challenging to determine, and this uncertainty can lead to inadequate healthcare services and treatments.

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Diabetic osteopathy is a frequent complication in patients with type 2 diabetes mellitus (T2DM). The association between T2DM and increased fracture risk has led to study the impact of new antidiabetic drugs on bone metabolism. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are incretin mimetic drugs which have many pleiotropic properties.

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As part of a surveillance plan active since the early 1990s, this study evaluates malignant mesothelioma (MM) mortality for the time-window 2010-2019 in Italy, a country that banned asbestos in 1992. National and regional mortality rates for MM, and municipal standardized mortality ratios (all mesotheliomas, pleural (MPM) and peritoneal (MPeM)), by gender and age group were calculated. A municipal clustering analysis was also performed.

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