Publications by authors named "E Cebelinski"
This paper describes the hybrid genome assembly of sucrose non-fermenting non-O1/non-O139 isolated from human soft tissue infection. The hybrid assembled genome comprises two circular chromosomes with lengths of 3,001,999 bp and 1,264,051 bp, respectively, with a G + C content of 47.38%.
View Article and Find Full Text PDFThe parasite Cryptosporidium hominis is a leading cause of the diarrheal disease cryptosporidiosis, whose incidence in the United States has increased since 2005. Here, we show that the newly emerged and hyper-transmissible subtype IfA12G1R5 is now dominant in the United States. In a comparative analysis of 127 newly sequenced and 95 published C.
View Article and Find Full Text PDFShiga toxin (Stx) is the definitive virulence factor of Shiga toxin-producing Escherichia coli (STEC). Stx variants are currently organized into a taxonomic system of three Stx1 (a, c, and d) and seven Stx2 (a, b, c, d, e, f, and g) subtypes. In this study, seven STEC isolates from food and clinical samples possessing sequences that do not fit current Shiga toxin taxonomy were identified.
View Article and Find Full Text PDFArticle Synopsis
- Cyclosporiasis, caused by the parasite Cyclospora cayetanensis, leads to watery diarrhea and has seen an increase in cases in the US, prompting public health agencies to enhance outbreak investigation tools.
- The CDC developed a new detection system using deep sequencing and machine learning to identify genetic clusters of the parasite, with initial evaluations showing promising effectiveness, though early versions faced bioinformatics limitations.
- Recent improvements to the CDC's genotyping system addressed previous issues, and testing confirmed its strong performance, with high sensitivity (90%) and specificity (99%), paving the way for a nationwide network for C. cayetanensis monitoring.
Background: Syndromic gastrointestinal multiplex polymerase chain reaction (PCR) panels (GMPPs) are used by an increasing number of clinical laboratories to identify enteric pathogens. species are included on GMPPs, but because of the low prevalence of vibriosis, performance characteristics for these panels have been difficult to measure.
Methods: All spp.