Publications by authors named "E Castro Osorio"
Background: High-resolution (HR) 3D MR images provide detailed soft-tissue information that is useful in assessing long-term side-effects after treatment in childhood cancer survivors, such as morphological changes in brain structures. However, these images require long acquisition times, so routinely acquired follow-up images after treatment often consist of 2D low-resolution (LR) images (with thick slices in multiple planes).
Purpose: In this work, we present a super-resolution convolutional neural network, based on previous single-image MRI super-resolution work, that can reconstruct a HR image from 2D LR slices in multiple planes in order to facilitate the extraction of structural biomarkers from routine scans.
Article Synopsis
- - The study focuses on the Amaryllidaceae alkaloids found in the subfamily Amaryllidoideae, specifically investigating their anticancer potential through histochemical methods and chromatographic analysis on the plant Regel.
- - It found that bulbs contain specific alkaloids like crinane and galanthamine, while roots have a significantly higher concentration of lycorine and galanthamine, indicating that roots produce more alkaloids overall.
- - The research indicates that the total alkaloid extracts from both bulbs and roots show a dose-dependent cytotoxic effect on human lung and gastric cancer cells, suggesting their potential as antiproliferative agents.
Edible flowers have been used since ancient times, but their potential for improving human health has not been explored. This study aimed to evaluate the profile of bioactive compounds (organic acids, phenolics, and carotenoids) and the antioxidant and antimicrobial activity of nine flower varieties with high concentrations of carotenoids or total phenolic compounds. Ninety-three edible flowers were analysed for physicochemical characteristics, total phenolic and carotenoid concentrations, and antioxidant activity (ABTS).
View Article and Find Full Text PDFThis study presents the synthesis and characterization of a series of 13 novel acetamides. These were subjected to Ellman's assay to determine the efficacy of the AChE and BChE inhibitors. Finally, we report their antioxidant activity as an alternative approach for the search for drugs to treat AD.
View Article and Find Full Text PDFObjectives: The aim of this study was to determine the viscoelastic performance and energy dissipation of conditioned dentin infiltrated with polymeric nanoparticles (NPs) doped with tideglusib (TDg) (TDg-NPs).
Methods: Dentin conditioned surfaces were infiltrated with NPs and TDg-NPs. Bonded interfaces were created, stored for 24 h and submitted to mechanical and thermal challenging.