Publications by authors named "E Carrasco-Marin"

Article Synopsis
  • - The COVID-19 pandemic has disrupted pregnancy management and work conditions, but little research has been done on how these changes impact pregnant women leaving work earlier and the effects on pregnancy outcomes
  • - A study in Cantabria, Spain, analyzed 760 women who were pregnant during 2020, looking specifically at factors that influenced whether they left work before the 26th week of pregnancy
  • - Findings revealed that factors like having a university degree, working in-person, being born outside Europe, and not smoking were linked to a lower likelihood of leaving work early, but leaving work earlier did not correlate with different pregnancy outcomes.
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Objectives: To investigate the functional consequences of IL10 (-592C/A and -1082A/G) gene polymorphisms and their association with susceptibility to, and disease phenotype, in patients with polymyalgia rheumatica (PMR).

Methods: A total number of 168 with PMR and 124 age-matched controls were genotyped using allele-specific primers and restriction fragment length polymorphism analysis. The levels of circulating IL10 and the production of IL10 by PBMCs after in vitro stimulation were studied by Cytometric Bead Array.

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Article Synopsis
  • Using live Listeria vaccines can be risky for people with weak immune systems, so researchers are looking into safer options.
  • They compared two types of immune cells, dendritic cells (DCs) and macrophages, to see which is better for use in vaccines against listeriosis.
  • The study found that DCs loaded with a specific protein (GAPDH1-22) offered better protection with fewer side effects than another protein (LLO), making it a promising candidate for new vaccines.
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Polymorphisms of cytokine genes have been investigated as susceptibility markers of giant cell arteritis (GCA). Here, we have reviewed the evidence to date and especially addressed the functional consequences of IL10 (-592C/A and -1082A/G) gene polymorphisms and their association with susceptibility to and disease phenotype in GCA. A total number of 71 patients with GCA and 124 age-matched controls were genotyped using allele-specific primers and restriction fragment length polymorphism analysis.

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Objective: To investigate whether there is association between the rs20541 (R130Q) polymorphism in the IL-13 gene with disease susceptibility and clinical subsets in patients with elderly-associated inflammatory chronic diseases.

Material And Methods: 78 patients with giant cell arteritis (GCA), 174 with polymyalgia rheumatica (PMR), 90 elderly-onset rheumatoid arthritis (EORA), and 465 healthy controls from the same geographic area were studied. The rs20541 (R130Q) polymorphism in the IL-13 gene was evaluated by PCR-RFLP.

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