[Hemodynamics, hemocoagulation and neuroendocrine responses in long-duration anesthesia. Comparison of propofol infusion with thiopentone and NLA II].

Ten patients receiving propofol for the induction and maintenance of anaesthesia were compared with 10 patients in whom anaesthesia was induced with thyopentone and maintained with fentanil. The cardiovascular response to anaesthesia, the effects on coagulation and fibrinolysis and the neuroendocrine response have been investigated during surgical procedures exceeding 90'. There was a larger decrease in PA after induction in the propofol group versus control, but the overall quality of anaesthesia during induction and maintenance was comparable in both groups.